6 edition of Gene Therapy for Cancer (Cancer Drug Discovery and Development) found in the catalog.
February 2, 2007
by Humana Press
Written in English
|Contributions||Kelly K. Hunt (Editor), Stephan A. Vorburger (Editor), Stephen G. Swisher (Editor)|
|The Physical Object|
|Number of Pages||600|
Gene therapy remains an expensive medical path, however. Moving it out of the laboratory and into the clinic will require innovative pricing schemes and regulatory policies. In this book various authors have highlighted specific genes that could be expressed, overexpressed, neutralised or h- nessed to achieve cancer control. The problem of transferring the therapeutic gene into the cancer cell has been partly addressed with major developments in the field of naked plasmid DNA, adenovirus, retrovirus and adeno.
This page contains a listing of cellular and gene therapy guidances. Guidance for Industry: Clinical Considerations for Therapeutic Cancer Vaccines . Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein.
Gene therapy research is not new. In fact, scientists have been investigating and evolving it for more than 50 years. Gene therapy research has the potential to find ways to treat many diseases; some of these diseases are partly or fully caused by genetic mutations, such as: Gene therapy versus cell therapy People may confuse gene therapy with File Size: KB. These companies have been followed up since they were the topic of a book on gene therapy companies by the author of this report. John Wiley & Sons published the book in and from to
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The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells.
The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the Gene Therapy for Cancer book technology in gene therapy and its therapeutic applications to the treatment of cancer.
The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific. A complete introduction and guide to the latest Gene Therapy for Cancer book in cancer gene therapy-from bench to bedside.
The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and Format: Hardcover.
Gene Therapy for cancer includes references up to and including This reflects the period of time that it takes to complete a multi-authored book.
One criticism is that as cancer gene therapy is a rapidly advancing technology, the developments of the last 3 years in this field are : S Schepelmann, C J Springer.
Despite the hope that gene therapy can be used to treat cancer, genetic diseases, and AIDS, there are concerns that the immune system may attack cells treated by gene therapy, that the viral vectors could mutate and become virulent, or that altered genes might be passed to succeeding generations.
In a few instances trials have been halted when. From the reviews of the second edition: “This book, authored by a number of prominent researchers in the field provides an overview of recent ground-breaking experimental and clinical concepts and protocols in cancer gene therapy.
the editors and authors are to be commended for producing a well-organised, authoritative and succinct coverage of the vast. “The Gene Therapy Plan is a comprehensive and practical approach to the science of epigenetics—and how to apply it to your life right now.
This book is a godsend that could save your life.” —Christiane Northrup, M.D., author of the New York Times bestseller Women’s Bodies, Women’s Wisdom/5(). Gene therapy introduces transgenic cells either into somatic tissue to correct defective function (somatic therapy) or into the germ line for transmission to descendants (germ-line therapy).
By agreement with the publisher, this book is accessible by. Advances in Cell and Gene Therapy is an international journal publishing original, high-quality, peer-reviewed articles which cover basic and clinical research relating to advances in cell, gene, and immune therapies and their use in the treatment of nonmalignant and neoplastic hematological diseases, as well as some non-hematological diseases.
The topics the journal. Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to.
Gene therapy has the potential to be a tailor-made therapeutic with increased specificity and decreased side effects that can offer a "cure" for many disorders. The aim of this book is to provide up-to-date reviews of the rapidly growing field of gene therapy.
Chapters cover a large range of topics including methods of gene delivery, and identification of targets with several Cited by: 8. The book has 67 contributors, mostly based in the United States. It contains over pages of text, divided into three parts: (1) vectors used Author: S Schepelmann, C J Springer.
A type of integrating gene therapy, known as CAR-T therapies, has already been approved to treat patients with certain kinds of leukemia and lymphoma.
An integrating gene therapy to treat CF is being tested in animals, and a clinical trial to test the safety of this therapy in people with CF could happen in the next several years.
Gene Therapy of Cancer: Methods and Protocols offers basic and clinical researchers a broad ranging overview and collection of the most recent advances in gene transfer techniques. Written by leading international authorities, its readily reproducible, cutting-edge methods constitute today's most valuable tools for the study of cancer gene.
The Promise of Gene Therapy Unfolds In many ways, was the year of gene therapy in the United States. Patients and pharmaceutical companies celebrated the approval of not one, but three treatments for otherwise untreatable health conditions. Researchers have been working on developing safe, effective gene therapies for three decades.
Early trials were. Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy. Reviews "The book is easy to read and is likely to be consulted by students, experienced researchers and medical practitioners alike.".
Although gene therapy is a promising treatment option for a number of diseases (including inherited disorders, some types of cancer, and certain viral infections), the technique remains risky and is still under study to make sure that it will be safe and effective.
Gene therapy is currently being tested only for diseases that have no other cures. The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer.
Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing. The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical Medicine Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell therapies.
gene therapy listen (jeen THAYR-uh-pee) A type of experimental treatment in which foreign genetic material (DNA or RNA) is inserted into a person's cells to prevent or fight disease. Gene therapy is being studied in the treatment of certain types of cancer. CAR-T gene therapy is a new treatment recently approved for use by the FDA for some forms of leukemia and non-Hodgkin lymphoma.
Dimas Padilla—a stage 4 cancer patient—joined one of the first.This could have damaging effects, for example, if it interferes with an important gene involved in regulating cell division, it could result in cancer.
The cost of gene therapy: Many genetic disorders that can be targeted with gene therapy are extremely rare. Gene therapy therefore often requires an individual, case-by-case approach.The book provides a comprehensive overview of the current state, and the new concepts for the future directions of modern cancer therapy.
Bringing together all the relevant aspects from basic and applied science, and the clinical experiences of this new direction in medicine, it is an up-to-date summary of the activities in the field and will be the basis for evaluating future progress in .